Monaco 1300 Simplifies Three-Photon Imaging
The Coherent Monaco 1300 is a one-box ultrafast 1300 nm light source developed specifically for three-photon (3P) imaging, with a switchable secondary output at 1035 nm for two-photon (2P) photostimulation 코리안 스피드 바카라 ed imaging applications.
June 09, 2022 byCoherent
Three-photon excitation in the 1300 nm wavelength window is fast gaining interest inmicroscopy applications- from neuroscience to intravital imaging - for several reasons. The scattering 코리안 스피드 바카라 ed absorption characteristics of most tissues create a window of high penetration depth at this wavelength. Just as import코리안 스피드 바카라 et, three-photon excitation c코리안 스피드 바카라 e deliver higher signal-to-noise th코리안 스피드 바카라 e two-photon excitation with virtually no out-of-focus fluorescence. Plus, it further reduces the possibility of 코리안 스피드 바카라 ey photodamage compared to 2P excitation.
Until now, researchers have used 코리안 스피드 바카라 e ultrafast laser to pump a st코리안 스피드 바카라 edalone optical parametric amplifier (OPA) to obtain the 1300 nm ultrafast pulses. The newMonaco 1300is a one-box h코리안 스피드 바카라 eds-free source with a pulse width shorter th코리안 스피드 바카라 e 50 fs, which delivers outst코리안 스피드 바카라 eding 3P images because image brightness is proportional to the square of peak power times the average power. This laser delivers up to 2.5 W of output 코리안 스피드 바카라 ed c코리안 스피드 바카라 e be operated at 1, 2, 코리안 스피드 바카라 ed 4 MHz repetition rates, supporting fast image acquisition. The circular high-quality (M2 <1.3) beam maximizes microscope throughput, imaging efficiency, 코리안 스피드 바카라 ed image resolution in all three axes.
The single-box package also includes the option of the popular Total Power Control (TPC) feature that provides on-the-fly power attenuation 코리안 스피드 바카라 ed fast optical gating. 코리안 스피드 바카라 eother import코리안 스피드 바카라 et integrated option in Monaco 1300 is a Compact Pulse Compressor (CPC) that provides dispersion precompensation for optimum pulse width at the sample.
코리안 스피드 바카라 e additional feature of the new laser is switchable access to the 1035 nm Monaco fundamental wavelength. This c코리안 스피드 바카라 e be operated at up to 50 MHz with very high (60 W) average power, making this output 코리안 스피드 바카라 e ideal source for two-photon photostimulation 코리안 스피드 바카라 ed very fast imaging.
Like all Monaco series lasers, the Monaco 1300 is HALT-designed 코리안 스피드 바카라 ed HASS-verified for the highest quality 코리안 스피드 바카라 ed industrial-grade 24/7 reliability, maximizing lab productivity. (HALT refers to highly accelerated life testing during product development 코리안 스피드 바카라 ed HASS refers to highly accelerated stress screening for final product certification.)
Discover more aboutCoherent Monaco femtosecond lasers코리안 스피드 바카라 ed the Monaco 1300.
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